論文一覧

2014年

Yoshizawa T, Karim MF, Sato Y, Senokuchi T, Miyata K, Fukuda T, Go C, Tasaki M, Uchimura K, Kadomatsu T, Tian Z, Smolka C, Sawa T, Takeya M, Tomizawa K, Ando Y, Araki E, Akaike T, Braun T, Oike Y, Bober E, Yamagata K. : SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway. Cell Metab 19 : 712-721, 2014

Shiraishi, N., Kitamura, K., Hayata, M., Ogata, T., Tajiri-Okamura, K., Nakayama, Y., Kohda, Y., Tomita, K., and Mukoyama, M. : Low-density lipoprotein apheresis for proteinuria in lupus nephritis with intraglomerular foam cells containing cholesterol crystals. Am. J. Kidney Dis., in press, 2014

Kuragano, T., Matsumura, O., Matsuda, A., Hara, T., Kiyomoto, H., Murata, T., Kitamura, K., Fujimoto, S., Hase, H., Joki, N., Fukatsu, A., Inoue, T., Itakura, I., and Nakanishi, T. : Association between hemoglobin variability, serum ferritin levels and mortality in maintenance hemodialysis patients. Kidney Int., 86: 845-854, 2014

Shiraishi,N., Kitamura, K., Kohda, Y., Iseki, K., and Tomita, K. : Prevalence and risk factor analysis of nephrosclerosis and ischemic nephropathy in the Japanese general population. Clin. Exp. Nephrol., 18: 461-468, 2014

Uchimura, K., Hayata, M., Mizumoto, T., Miyasato, Y., Kakizoe, Y., Morinaga, J., Onoue, T., Yamazoe, R., Ueda, M., Adachi, M., Miyoshi, T., Shiraishi, N., Ogawa, W., Fukuda, K., Kondo, T., Matsumura, T., Araki, E., Tomita, K., and Kitamura, K. : The serine protease prostasin regulates hepatic insulin sensitivity by modulating TLR4 signaling. Nat. Commun., 5: 3428, 2014

Ichijo S, Furuya F, Shimura H, Hayashi Y, Takahashi K, Ohta K, Kobayashi T, Kitamura K : Activation of the RhoB Signaling Pathway by Thyroid Hormone Receptor β in Thyroid Cancer Cells. PLoS ONE 9 : e116252, 2014

Furuya F, Shimura H, Yokomichi H, Takahashi K, Akiyama D, Asakawa C, Okamura A, Motosugi A, Haraguchi K, Yamagata Z, Kobayashi T : Neutrophil gelatinase-associated lipocalin levels associated with cardiovascular disease in chronic kidney disease patients. Clin Exp Nephrol 18 : 778-783, 2014

Arase Y, Kobayashi M, Kawamura Y, Suzuki F, Suzuki Y, Akuta N, Kobayashi M, Sezaki H, Saito S, Hosaka T, Ikeda K, Kumada H, Kobayashi T : Impact of virus clearance for the development of hemorrhagic stroke in chronic hepatitis C. J Med Virol 86 : 169-175, 2014

Takahashi K, Furuya F, Shimura H, Kaneshige M, Kobayashi T : Impaired oxidative endoplasmic reticulum stress response caused by deficiency of thyroid hormone receptor α. J Biol Chem 289 : 12485-12493, 2014

Aida K, Saitoh S, Nishida Y, Yokota S, Ohno S, Mao X, Akiyama D, Tanaka S, Awata T, Shimada A, Oikawa Y, Shimura H, Furuya F, Takizawa S, Ichijo M, Ichijo S, Itakura J, Fujii H, Hashiguchi A, Takasawa S, Endo T, Kobayashi T : Distinct cell clusters touching islet cells induce islet cell replication in association with over-expression of regenerating gene (REG) protein in fulminant type 1 diabetes. PLoS ONE 9 : e95110, 2014

Nishida Y, Aida K, Kihara M, Kobayashi T :  Antibody-validated proteins in inflamed islets of fulminant type 1 diabetes profiled by laser-capture microdissection followed by mass spectrometry. PLoS ONE 9 : e107664, 2014

Furuya F, Shimura H, Takahashi K, Akiyama D, Motosugi A, Ikegishi Y, Haraguchi K, Kobayashi T : Skin autofluorescence is a predictor of cardiovascular disease in chronic kidney disease patients. Ther Apher Dial 19 : 40-44, 2014

2013年

Morinaga, J., Kakizoe, Y., Miyoshi, T., Onoue, T., Ueda, M., Mizumoto, T., Yamazoe, R., Uchimura, K., Hayata, M., Shiraishi, N., Adachi, M., Sakai, Y., Tomita, K., and Kitamura, K. : The antifibrotic effect of a serine protease inhibitor in the kidney. Am. J. Physiol. (Renal Physiol.), 305: F173-181, 2013

Olivieri, O., Chiecchi, L., Pizzolo, F., Castagna, A., Raffaelli, R., Gunasekaran, M., Guarini, P., Consoli, L., Salvagno, G., and Kitamura, K. : Urinary prostasin in normotensive individuals: correlation with the aldosterone to renin ratio and urinary sodium. Hypertens. Res., 36: 528-533, 2013

Wakui, H., Tamura, K., Masuda, S., Tsurumi-Ikeya, Y., Fujita, M., Maeda, A., Ohsawa, M., Azushima, K., Uneda, K., Matsuda, M., Kitamura, K., Uchida, S., Toya, Y., Kobori, H., Nagahama, K., Yamashita, A., and Umemura, S. : Enhanced angiotensin receptor-associated protein in renal tubule suppresses angiotensin-dependent hypertension. Hypertension, 61: 1203-1210, 2013

Ushio-Yamana, H., Minegishi, S., Ishigami, T., Araki, N., Umemura, M., Tamura, K., Maeda, E., Kakizoe, Y., Kitamura, K., and Umemura, S. : Renin angiotensin antagonists normalize aberrant activation of epithelial sodium channels in sodium-sensitive hypertension. Nephron Exp. Nephrol., 122: 95-102, 2013

Tanaka S, Aida K, Nishida Y, Kobayashi T : Pathophysiological mechanisms involving aggressive islet cell destruction in fulminant type 1 diabetes. Endocr J 60 : 837-845, 2013

Endo T, Kobayashi T : Immunization of mice with a newly identified thyroid-stimulating hormone receptor splice variant induces Graves'-like disease. J Autoimmun 43 : 18-25, 2013

Awata T, Yamashita H, Kurihara S, Morita-Ohkubo T, Miyashita Y, Katayama S, Kawasaki E, Tanaka S, Ikegami H, Maruyama T, Shimada A, Takahashi K, Kawabata Y, Kobayashi T, Nishida N, Mawatari Y : A low-frequency GLIS3 variant associated with resistance to Japanese type 1 diabetes. Biochem Biophys Res Commun 437 : 521-525, 2013

Endo T, Kobayashi T : Concurrent overexpression of RET/PTC1 and TTF1 confers tumorigenicity to thyrocytes. Endocr Relat Cancer 20 : 767-776, 2013

Endo T, Kobayashi T : Excess TSH causes abnormal skeletal development in young mice with hypothyroidism via suppressive effects on the growth plate. Am J Physiol Endocrinol Metab 305 : E660-E666, 2013

Arase Y, Kobayashi M, Suzuki F, Suzuki Y, Kawamura Y, Akuta N, Kobayashi M, Sezaki H, Saito S, Hosaka T, Ikeda K, Kumada H, Kobayashi T : Effect of type 2 diabetes on risk for malignancies includes hepatocellular carcinoma in chronic hepatitis C. Hepatology 57 : 964-973, 2013

Arase Y, Kawamura Y, Seko Y, Kobayashi M, Suzuki F, Suzuki Y, Akuta N, Kobayashi M, Sezaki H, Saito S, Hosaka T, Ikeda K, Kumada H, Ohmoto-Sekine Y, Hsieh SD, Amakawa K, Ogawa K, Matsumoto N, Iwao A, Tsuji H, Hara S, Mori Y, Okubo M, Sone H, Kobayashi T : Efficacy and safety in sitagliptin therapy for diabetes complicated by non-alcoholic fatty liver disease. Hepatol Res 43 : 1163-1168, 2013

2012年

Kadowaki, D., Sumikawa, S., Arimizu, K., Taguchi, K., Kitamura, K., Ishitsuka, Y., Narita, Y., Irie, T., Chuang, V.T., Maruyama, T., Otagiri, M., and Hirata, S. : Effect of acetaminophen on the progression of renal damage in adenine induced renal failure model rats. Life Sci., 91: 1304-1308, 2012

Hayata, M., Kakizoe, Y., Uchimura, K., Morinaga, J., Yamazoe, R., Mizumoto, T., Onoue, T., Ueda, M., Shiraishi, N., Adachi, M., Miyoshi, T., Sakai, Y., Tomita, K., and Kitamura, K. : Effect of a serine protease inhibitor on the progression of chronic renal failure. Am. J. Physiol. (Renal Physiol.), 303: F1126-1135, 2012

Uchimura, K., Kakizoe, Y., Onoue, T., Hayata, M., Morinaga, J., Yamazoe, R., Ueda, M., Mizumoto, T., Adachi, M., Miyoshi, T., Shiraishi, N., Sakai, Y., Tomita, K., and Kitamura, K. : In vivo contribution of serine proteases to the proteolytic activation of γENaC in aldosterone-infused rats. Am. J. Physiol. (Renal Physiol.), 303: F939-943, 2012

Shiraishi, N., Kitamura, K., Hayata, M., Ogata, T., Adachi, M., Kajiwara, K., Ikeda, H., Miyoshi, T., and Tomita, K. : Case of anti-glomerular basement membrane antibody-induced glomerulonephritis with cytomegalovirus-induced thrombotic microangiopathy. Intern. Med. J., 42: e7-11, 2012

Kitamura, K. and Tomita, K. : Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension. Clin. Exp. Nephrol., 16: 44-48, 2012

Arase Y, Kobayashi M, Suzuki F, Suzuki Y, Kawamura Y, Akuta N, Imai N, Kobayashi M, Sezaki H, Matsumoto N, Saito S, Hosaka T, Ikeda K, Kumada H, Ohmoto Y, Amakawa K, Hsieh SD, Ogawa K, Tanabe M, Tsuji H, Kobayashi T : Difference in malignancies of chronic liver disease due to non-alcoholic fatty liver disease or hepatitis C in Japanese elderly patients. Hepatol Res 42 : 264-272, 2012

Matsumoto N, Arase Y, Seko Y, Imai N, Kawamura Y, Sezaki H, Hosaka T, Akuta N, Kobayashi M, Kobayashi M, Suzuki Y, Saito S, Suzuki F, Ikeda K, Kumada H, Aida K, Kobayashi T : Prevalence and predictive factors of diabetes in hepatitis virus positive liver cirrhosis with fasting plasma glucose level of <126 mg/dL. Hepatol Res 42 : 558-563, 2012

Endo T, Kobayashi T : Expression of functional TSH receptor in white adipose tissues of hyt/hyt mice induces lipolysis in vivo. Am J Physiol Endocrinol Metab 302 : E1569-1575, 2012

Endo T, Kobayashi T : Dominant negative effect of mutated thyroid stimulating hormone receptor (P556L) causes hypothyroidism in C. RF-Tshrhyt/wild mice. PLoS One 7 : e42358, 2012

Shimura H, Itoh K, Sugiyama A, Ichijo S, Ichijo M, Furuya F, Nakamura Y, Kitahara K, Kobayashi K, Yukawa Y, Kobayashi T : Absorption of radionuclides from the Fukushima nuclear accident by a novel algal strain. PLoS One 7 : e44200, 2012

Imagawa A, Hanafusa T, Awata T, Ikegami H, Uchigata Y, Osawa H, Kawasaki E, Kawabata Y, Kobayashi T, Shimada A, Shimizu I, Takahashi K, Nagata M, Makino H, Maruyama T : Report of the committee of the Japan diabetes society on the research of fulminant and acute-onset type 1 diabetes mellitus : New diagnostic criteria of fulminant type 1 diabetes mellitus (2012). Diabetol Int 3 : 179-183, 2012

Onuma H, Tohyama M, Imagawa A, Hanafusa T, Kobayashi T, Kano Y, Ohashi J, Hashimoto K, Osawa H, Makino H : High frequency of HLA B62 in fulminant type 1 diabetes with the drug-induced hypersensitivity syndrome. J Clin Endocrinol Metab 97 : E2277-E2281, 2012

2011年

Tasic, V., Hynes, A.M., Kitamura, K., Cheong, H.I., Lozanovski, V.J., Gucev, Z., Jutabha, P., Anzai, N., and Sayer, J.A. : Clinical and functional characterization of URAT1 variants. PLoS One, 6: e28641, 2011

Adachi, M., Miyoshi, T., Shiraishi, N., Shimada, H., Sakaguchi, S., Tomita, K., and Kitamura, K. : A study of maintenance therapy after intravenous maxacalcitol for secondary hyperparathyroidism. Clin. Nephrol., 76: 266-272, 2011

Anraku, M., Takeuchi, K., Watanabe, H., Kadowaki, D., Kitamura, K., Tomita, K., Kuniyasu, A., Suenaga, A., Maruyama, T., and Otagiri, M. : Quantitative analysis of cysteine-34 on the anitioxidative properties of human serum albumin in hemodialysis patients. J. Pharm. Sci., 100: 3968-3976, 2011

Aida K, Nishida Y, Tanaka S, Maruyama T, Shimada A, Awata T, Suzuki M, Shimura H, Takizawa S, Ichijo M, Akiyama D, Furuya F, Kawaguchi A, Kaneshige M, Itakura J, Fujii H, Endo T, Kobayashi T : RIG-I- and MDA5-initiated innate immunity linked with adaptive immunity accelerates β-cell death in fulminant type 1 diabetes. Diabetes 60 : 884-889, 2011

Arase Y, Suzuki F, Kobayashi M, Suzuki Y, Kawamura Y, Matsumoto N, Akuta N, Imai N, Kobayashi M, Sezaki H, Saito S, Hosaka T, Ikeda K, Kumada H, Ohmoto Y, Amakawa K, Tsuji H, Hsieh SD, Kobayashi T : Efficacy and safety in sitagliptin therapy for diabetes complicated by chronic liver disease caused by hepatitis C virus. Hepatol Res 41 : 524-529, 2011

Arase Y, Suzuki F, Kobayashi M, Suzuki Y, Kawamura Y, Matsumoto N, Akuta N, Kobayashi M, Sezaki H, Saito S, Hosaka T, Ikeda K, Kumada H, Ohmoto Y, Amakawa K, Tsuji H, Hsieh SD, Kato K, Tanabe M, Ogawa K, Hara S, Kobayashi T : The development of chronic kidney disease in Japanese patients with non-alcoholic fatty liver disease. Intern Med 50 : 1081-1087, 2011

Nakamura K, Kawasaki E, Imagawa A, Awata T, Ikegami H, Uchigata Y, Kobayashi T, Shimada A, Nakanishi K, Makino H, Maruyama T, Hanafusa T, the research committee on type 1 diabetes of the Japan diabetes society : Type 1 diabetes and interferon therapy : A nationwide survey in Japan. Diabetes Care 34 : 2084-2089, 2011.

Endo T, Kobayashi T : Thyroid-specific gene expression in chondrocytes. Biochem Biophys Res Commun 416 : 227-231, 2011

Kobayashi T, Nishida Y, Tanaka S, Aida K : Pathological changes in the pancreas of fulminant type 1 diabetes and slowly progressive insulin-dependent diabetes mellitus (SPIDDM): innate immunity in fulminant type 1 diabetes and SPIDDM. Diabetes Metab Res Rev 27 : 965-970, 2011

2010年

Ko, T., Kakizoe, Y., Wakida, N., Hayata, M., Uchimura, K., Shiraishi, N., Miyoshi, T., Adachi, M., Aritomi, S., Konda, T., Tomita, K., and Kitamura, K. : Regulation of adrenal aldosterone production by serine protease prostasin. J. Biomed. Biotechnol., 2010: 793843, 2010

Jutabha, P., Anzai, N., Kitamura, K., Taniguchi, A., Kaneko, S., Yan, K., Yamada, H., Shimada, H., Kimura, T., Katada, T., Fukutomi, T., Tomita, K., Urano, W., Yamanaka. H., Seki, G., Fujita, T., Moriyama, Y., Yamada, A., Uchida, S., Wempe, M. F., Endou, H., and Sakurai, H. : Human sodiumphosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate. J. Biol. Chem., 285: 35123-35132, 2010

Kitamura, K. and Tomita, K. : Regulation of renal sodium handling through the interaction between serine proteases and serine protease inhibitors. Clin. Exp. Nephrol., 14: 405-410, 2010

Chai, K., Kitamura, K., McCann, A., and Wu, X.R. : The epithelium-molecular landscaping for an interactive barrier. J. Biomed. Biotechnol., 2010: 870506, 2010

Arase Y, Suzuki F, Suzuki Y, Akuta N, Kobayashi M, Sezaki H, Hosaka T, Kawamura Y, Yatsuji H, Hirakawa M, Ikeda K, Hsieh SD, Oomoto Y, Amakawa K, Kato H, Kazawa T, Tsuji H, Kobayashi T, Kumada H : Virus clearance reduces bone fracture in postmenopausal women with osteoporosis and chronic liver disease caused by hepatitis C virus. J Med Virol 82 : 390-395, 2010

Koga M, Murai J, Saito H, Kasayama S, Imagawa A, Hanafusa T, Kobayashi T, the members of the Japan diabetes society's committee on research on type 1 diabetes : Serum glycated albumin to haemoglobin A1C ratio can distinguish fulminant type 1 diabetes mellitus from type 2 diabetes mellitus. Ann Clin Biochem 47 : 313-317, 2010

Endo T, Kobayashi T : Runx2 deficiency in mice causes decreased thyroglobulin expression and hypothyroidism. Mol Endocrinol 24 : 1267-1273, 2010

Furuya F, Shimura H, Yamashita S, Endo T, Kobayashi T : Liganded thyroid hormone receptor-α enhances proliferation of pancreatic β-cells. J Biol Chem 285 : 24477-24486, 2010

2009年

Sugahara, T., Koga, T., Ueno-Shuto, K., Shuto, T., Watanabe, E., Maekawa, A., Kitamura, K., Tomita, K., Mizuno, A., Sato, T., Suico, M. A., and Kai, H. : Calreticulin positively regulates the expression and function of epithelial sodium channel. Exp. Cell Res., 315: 3294-3300, 2009

Kakizoe, Y., Kitamura, K., Ko, T., Wakida, N., Maekawa, A., Miyoshi, T., Shiraishi, N., Adachi, M., Zhang, Z., Masilamani, S., and Tomita, K. : Aberrant ENaC activation in Dahl salt-sensitive rats. J. Hypertens., 27: 1679-1689, 2009

Maekawa, A., Kakizoe, Y., Miyoshi, T., Wakida, N., Ko, T., Shiraishi, N., Adachi, M., Tomita, K., and Kitamura, K. : Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension. J. Hypertens., 27: 181-189, 2009

Koda, A., Wakida, N., Toriyama, K., Yamamoto, K., Iijima, H., Tomita, K., and Kitamura, K. : Urinary prostasin in humans: relationships among prostasin, aldosterone and epithelial sodium channel activity. Hypertens. Res., 32: 276-281, 2009

Nonoguchi, H., Kohda, Y., Fukutomi, R., Nakayama, Y., Naruse, M., Kitamura, K., Inoue, T., Nakanishi, T., and Tomita, K. : A case with acute renal failure and subsequent nephrotic syndrome. Ren. Fail., 31: 162-166, 2009

Awata T, Kawasaki E, Tanaka S, Ikegami H, Maruyama T, Shimada A, Nakanishi K, Kobayashi T, Iizuka H, Uga M, Kawabata Y, Kanazawa Y, Kurihara S, Osaki M, Katayama S, on behalf of the Japanese study group on type 1 diabetes genetics : Association of type 1 diabetes with two Loci on 12q13 and 16p13 and the influence coexisting thyroid autoimmunity in Japanese. J Clin Endocrinol Metab 94 : 231-235, 2009

Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, Tanaka S, Kanazawa Y, Eguchi K, the Japanese study group on type 1 diabetes genetics : Genetic association between the interleukin-2 receptor-α gene and mode of onset of type 1 diabetes in the Japanese population. J Clin Endocrionl Metab 94 : 947-952, 2009

Endo T, Takizawa S, Tanaka S, Takahashi M, Fujii H, Kamisawa T, Kobayashi T : Amylase -2A autoantibodies : Novel marker of autoimmune pancreatitis and fulminant type 1 diabetes. Diabetes 58 : 732-737, 2009

Takizawa S, Endo T, Wanjia X, Tanaka S, Takahashi M, Kobayashi T : HSP 10 is a new autoantigen in both autoimmune pancreatitis and fulminant type 1 diabetes. Biochem Biophys Res Commun 386 : 192-196, 2009

Haraguchi K, Hara S, Ubara Y, Tanaka S, Nukui I, Shimura H, Ohashi K, Kobayashi T : Complete remission of diabetic nephropathy in a type 1 diabetic patient with near-nephrotic range proteinuria and reduced renal function. Diabetes Res Clin Pract 83 : 295-299, 2009

Arase Y, Suzuki F, Ikeda K, Kumada H, Tsuji H, Kobayashi T : Multivariate analysis of risk factors for the development of type 2 diabetes in nonalcoholic fatty liver disease. J Gastroenterol 44 : 1064-1070, 2009

Arase Y, Suzuki F, Suzuki Y, Akuta N, Kobayashi M, Kawamura Y, Yatsuji H, Sezaki H, Hosaka T, Hirakawa M, Saito S, Ikeda K, Kobayashi M, Kumada H, Kobayashi T : Losartan reduces the onset of type 2 diabetes in hypertensive Japanese patients with chronic hepatitis C. J Med Virol 81 : 1584-1590, 2009

Endo T, Kobayashi T : Immunization with thyroglobulin induces Graves'-like disease in mice. J Endocrinol 202 : 217-222, 2009

Tanaka S, Nishida Y, Aida K, Maruyama T, Shimada A, Suzuki M, Shimura H, Takizawa S, Takahashi M, Akiyama D, Arai-Yamashita S, Furuya F, Kawaguchi A, Kaneshige M, Katoh R, Endo T, Kobayashi T : Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit : A mechanism of accelerated β-cell failure in fulminant type 1 diabetes. Diabetes 58 : 2285-2291, 2009

Kawabata Y, Ikegami H, Awata T, Imagawa A, Maruyama T, Kawasaki E, Tanaka S, Shimada A, Osawa H, Kobayashi T, Hanafusa T, Tokunaga K, Makino H, on behalf of the committee on type 1 diabetes, Japan diabetes society : Differential association of HLA with three subtypes of type 1 diabetes : Fulminant, slowly progressive and acute-onset. Diabetologia 52 : 2513-2521, 2009

Ogata R, Hiramatsu N, Hayakawa K, Nakajima S, Yao J, Kobayashi T, Kitamura M : Impairment of MCP-1 expression in mesothelial cells exposed to peritoneal dialysis fluid by osmotic stress and acidic stress. Perit Dial Int 31 : 80-89, 2009

2008年

Anraku, M., Kitamura, K. (equal contribution), Shintomo, R., Takeuchi, K., Ikeda, H., Nagano, J., Ko, T., Mera, K., Tomita, K., and Otagiri, M. : Effect of intravenous iron administration frequency on AOPP and inflammatory biomarkers in chronic hemodialysis patients: a pilot study. Clin. Biochem., 41: 1168-1174, 2008

Anzai, N., Ichida, K., Jutabha, P., Kimura, T., Babu, E., Jin, C.J., Srivastava, S., Kitamura, K., Hisatome, I., Endou, H., and Sakurai, H. : Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. J. Biol. Chem., 283: 26834-26838, 2008

Iwao, Y., Nakajou, K., Nagai, R., Kitamura, K., Anraku, M., Maruyama, T., and Otagiri, M. : CD36 is one of important receptors promoting renal tubular injury by advanced oxidation protein products. Am. J. Physiol. (Renal Physiol.), 295: F1871-F1880, 2008

Nonoguchi, H., Kiyama, S., Kitamura, K., Naruse, M., Tomita, M., Tazoe, N., Tajiri, M., Nakayama, Y., Kohda, Y., Inoue, T., and Tomita, K. : Long-term plasma levels and dose modulation of alacepril in patients with chronic renal failure. Hypertens Res., 31: 29-36, 2008

Kazama Y, Takamura T, Sakurai M, Shindo H, Ohkubo E, Aida K, Harii N, Taki K, Kaneshige M, Tanaka S, Shimura H, Endo T, Kobayashi T : New insulin sensitivity index from the oral glucose tolerance test. Diabetes Res Clin Pract 79 : 24-30, 2008

Maruyama T, Tanaka S, Shimada A, Funae O, Kasuga A, Kanatsuka A, Takei I, Yamada S, Harii N, Shimura H, Kobayashi T : Insulin intervention in slowly progressive insulin- dependent (type 1) diabetes mellitus. J Clin Endocrinol Metab 93 : 2115-2121, 2008

Endo T, Kobayashi T : Thyroid-stimulating hormone receptor in brown adipose tissue is involved in the regulation of thermogenesis. Am J Physiol Endocrionol Metab 295 : E514-E518, 2008

Endo T, Ohta K, Kobayashi T : Expression and function of Cbfa-1/Runx2 in thyroid papillary carcinoma cells. J Clin Endocrinol Metab 93 : 2409-2412, 2008

Takaike H, Uchigata Y, Iwamoto Y, Imagawa A, Iwahashi H, Kanatsuka A, Kawasaki E, Kobayashi T, Shimada A, Shimizu I, Maruyama T, Hanafusa T, Makino H : Nationwide survey to compare the prevalence of transient elevation of liver transaminase during treatment of diabetic ketosis or ketoacidosis in new-onset acute and fulminant type 1 diabetes mellitus. Ann Med 40 : 395-400, 2008

Shimada A, Kanazawa Y, Motohashi Y, Yamada S, Maruyama T, Ikegami H, Awata T, Kawasaki E, Kobayashi T, Nakanishi K, Kawabata Y, Kurihara S, Uga M, Tanaka S, the Japanese study group on type 1 diabetes genetics : Evidence for association between vitamin D receptor BsmI polymorphism and type 1 diabetes in Japanese. J Autoimmun 30 : 207-211, 2008

Imagawa A, Hanafusa T, Iwahashi H, Uchigata Y, Kanatsuka A, Kawasaki E, Kobayashi T, Shimada A, Shimizu I, Maruyama T, Makino H : Uniformity in clinical and HLA-DR status regardless of age and gender within fulminant type 1 diabetes. Diabetes Res Clin Pract 82 : 233-237, 2008

Hardt PD, Ewald N, Bröckling K, Tanaka S, Endo T, Kloer HU, Bretzel RG, Jaeger C, Shimura H, Kobayashi T : Distinct autoantibodies against exocrine pancreatic antigens in European patients with type 1 diabetes mellitus and non-alcoholic chronic pancreatitis. JOP 9 : 683-689, 2008

2007年

Shimoishi, K., Anraku, M., Kitamura, K., Tasaki, Y., Taguchi, K., Hashimoto, M., Fukunaga, E., Maruyama, T., and Otagiri, M. : An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure. Pharm. Res., 24: 1283-1289, 2007

Kadowaki, D., Anraku, M., Tasaki, Y., Kitamura, K., Wakamatsu, S., Tomita, K., Gebicki, J. M., Maruyama, T., and Otagiri, M. : Effect of olmesartan on oxidative stress in hemodialysis patients. Hypertens. Res., 30: 395-402, 2007

Murase Y, Imagawa A, Hanafusa T, Iwahashi H, Uchigata Y, Kanatsuka A, Kawasaki E, Kobayashi T, Shimada A, Shimizu I, Maruyama T, Makino H : Fulminant type 1 diabetes as a high risk group for diabetic microangiopathy-a nationwide 5-year-study in Japan. Diabetologia 50 : 531-537, 2007

Awata T, Kawasaki E, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Iizuka H, Kurihara S, Osaki M, Uga M, Kawabata Y, Tanaka S, Kanazawa Y, Katayama S, on behalf of the Japanese study group on type 1 diabetes genetics : Insulin gene/IDDM2 locus in Japanese type 1 diabetes : Contribution of class I alleles influence of class I subdivision in susceptibility to type 1 diabetes. J Clin Endocrinol Metab 92 : 1791-1795, 2007

Kobayashi T, Tanaka S, Shimada A, Maruyama T : High titer of autoantibodies to GAD identifies a specific phenotype of adult-onset autoimmune diabetes : Response to Buzzetti et al. Diabetes Care 30 : e126, 2007

2006年

Wakida, N., Kitamura, K., Tuyen, D.G., Maekawa, A., Miyoshi, T., Adachi, M., Shiraishi, N., Ko, T., Ha, V., Nonoguchi, H., and Tomita, K. : Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-β1 and aldosterone. Kidney Int., 70: 1432-1438, 2006

Shiraishi, N., Kitamura, K., Miyoshi, T., Adachi, M., Kohda, Y., Nonoguchi, H., Misumi, S., Maekawa, Y., Murayama, T., Tomita, M., and Tomita, K. : Successful treatment of a patient with severe calcific uremic arteriolopathy (calciphylaxis) by etidronate disodium . Am. J. Kidney Dis., 48: 151-154, 2006

Haraguchi K, Kubo M, Saito T, Furuya F, Inoue H, Takahashi M, Shimura H, Tago K, Kobayashi T : Serum level of macrophage colony-stimulating factor and atherosclerosis in hemodialysis patients. Nephron Clin Pract 102 : c14-20, 2006

Shimizu I, Makino H, Imagawa A, Iwahashi H, Uchigata Y, Kanatsuka A, Kawasaki E, Kobayashi T, Shimada A, Maruyama T, Hanafusa T : Clinical and immunogenetic characteristics of fulminant type 1 diabetes associated with pregnancy. J Clin Endocrinol Metab 91 : 471-476, 2006

Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, Tanaka S, Kanazawa Y, Lee I, Eguchi K, Japanese Study Group on Type 1 Diabetes Genetics: Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22): Association between a promoter polymorphism and type 1 diabetes in Asian populations. Am J Med Genet A 140 : 586-593, 2006

Murayama H, Matsuura N, Kawamura T, Maruyama T, Kikuchi N, Kobayashi T, Nishibe F, Nagata A : A sensitive radioimmunoassay of insulin autoantibody : Reduction of non-specific binding of [125I]insulin. J Autoimmun 26 : 127-32, 2006

Ikegami H, Awata T, Kawasaki E, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Amemiya S, Kawabata Y, Kurihara S, Tanaka S, Kanazawa Y, Mochizuki M, Ogihara T, on behalf of the Japanese study group on type 1 diabetes genetics : The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: A multicenter collaborative study in Japan. J Clin Endocrinol & Metab 91 : 1087-1092, 2006

2005年

Nagano, J., Kitamura, K., Hujer, K.M., Ward, C.J., Bram, R.J., Hopfer, U., Tomita, K., Huang, C., and Miller, R.T. : Fibrocystin Interacts with CAML, a protein involved in Ca2+ signaling. Biochem. Biophys. Res. Commun., 338: 880-889, 2005

Shimada, H., Kitamura, K. (equal contribution), Anraku, M., Miyoshi, T., Adachi, M., Tuyen, D.G., Wakamatsu, S., Nonoguchi, H., Tanaka, M., and Tomita, K. : Effect of telmisartan on ambulatory blood pressure monitoring, plasma brain natriuretic peptide, and oxidative status of serum albumin in hemodialysis patients. Hypertens. Res., 28: 987-994, 2005

Mera, K., Anraku, M., Kitamura, K., Nakajou, K., Maruyama, T., Tomita, K., and Otagiri, M. : Oxidation and carboxyl methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients. Hypertens. Res., 28: 973-980, 2005

Mera, K., Anraku, M., Kitamura, K., Nakajou, K., Maruyama, T., and Otagiri, M. : The structure and function of oxidized albumin in hemodialysis patients: Its role in elevated oxidative stress via neutrophil burst. Biochem. Biophys. Res. Commun., 334: 1322-1328, 2005

Wakida, N., Tuyen, D.G., Adachi, M., Miyoshi, T., Nonoguchi, H., Oka, T., Ueda, O., Tazawa, M., Kurihara, S., Yoneta, Y., Shimada, H., Oda, T., Kikuchi, Y., Matsuo, H., Hosoyamada, M., Endou, H., Otagiri, M., Tomita, K., and Kitamura, K. : Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia. J. Clin. Endocrinol. Metab., 90: 2169-2174, 2005

Furuhashi, M., Kitamura, K., Adachi, M., Miyoshi, T., Wakida, N., Ura, N., Shikano, Y., Shinshi, Y., Sakamoto, K., Hayashi, M., Satoh, N., Nishitani, T., Tomita, K., Shimamoto, K. : Liddle's syndrome caused by a novel mutation in the proline-rich PY motif of the epithelial sodium channel β-subunit. J. Clin. Endocrinol. Metab., 90: 340-344, 2005

Tuyen, D.G., Kitamura, K., Adachi, M., Miyoshi, T., Wakida, N., Nagano, J., Nonoguchi, H., and Tomita, K. : Inhibition of prostasin expression by TGF-β1 in renal epithelial cells. Kidney Int., 67: 193-200, 2005

Kitamura, K. and Tomita, K. : Familial pseudohyperkalemia: a rare syndrome, but diverse genetic heterogeneity. Intern Med., 44: 781-782, 2005

Imagawa A, Hanafusa T, Uchigata Y, Kanatsuka A, Kawasaki E, Kobayashi T, Shimada A, Shimizu I, Maruyama T, Makino H : Different contribution of class II HLA in fulminant and typical autoimmune type 1 diabetes mellitus. Diabetologia 48 : 294-300, 2005

Shimura H, Haraguchi K, Hiejima Y, Fukunari N, Fujimoto Y, Katagiri M, Koyanagi N, Kurita T, Miyakawa M, Miyamoto Y, Suzuki N, Suzuki S, Kanbe M, Kato Y, Murakami T, Tohno E, Tsunoda-Shimizu H, Yamada K, Ueno E, Kobayashi K, Kobayashi T, Yokozawa T, Kitaoka M : Distinct Diagnostic criteria for ultrasonographic examination of papillary thyroid carcinoma : a multicenter study. Thyroid 15 : 251-258, 2005

2004年

Anraku, M., Kitamura, K. (equal contribution), Shinohara, A., Adachi, M., Suenaga, A., Maruyama, T., Miyanaka, K., Miyoshi, T., Shiraishi, N., Nonoguchi, H., Otagiri, M., and Tomita, K. : Intravenous iron administration induces oxidation of serum albumin in hemodialysis patients. Kidney Int., 66: 841-848, 2004

2003年

Okumura, Y., Nishikawa, M., Cui, P., Shiota, M., Nakamura, Y., Adachi, M., Kitamura, K., Tomita, K., and Kido, H. : Cloning and characterization of a transmembrane-type serine protease from rat kidney, a new sodium channel activator. Biol. Chem., 384: 1483-1495, 2003

Iwashita, K., Kitamura, K., Narikiyo, T., Adachi, M., Shiraishi, N., Miyoshi, T., Nagano, J., Tuyen, D.G., Nonoguchi, H., and Tomita, K. : Inhibition of prostasin secretion by serine protease inhibitors in the kidney. J. Am. Soc. Nephrol., 14: 11-16, 2003

Shiraishi, N., Kitamura, K., Kohda, Y., Narikiyo, T., Adachi, M., Miyoshi, T., Iwashita, K., Nonoguchi, H., Miller, R.T., and Tomita, K. : Increased endothelin-1 expression in the kidney in hypercalcemic rats. Kidney Int., 63: 845-852, 2003

Nonoguchi, H., Kiyama, S., Inoue, H., Nakayama, Y., Inoue, T., Kohda, Y., Machida, K., Tajima, A., Kitamura, K., Miyoshi, T., Shimada, H., Shimada, H., Tajiri, M., Honda, Y., Tanaka, M., and Tomita, K. : Angiotensin-converting enzyme inhibitor withdrawal and ACE gene polymorphism. Clin. Nephrol., 60: 225-232, 2003

Tanaka, M., Itoh, K., Matsushita, K., Matsushita, K., Wakita, N., Adachi, M., Nonoguchi, H., Kitamura, K., Hosoyamada, M., Endou, H., and Tomita, K. : Two male siblings with hereditary renal hypouricemia and exercise-induced ARF. Am. J. Kidney Dis., 42:1287-1292, 2003

2002年

Narikiyo, T., Kitamura, K., Adachi, M., Miyoshi, T., Iwashita, K., Shiraishi, N., Nonoguchi, H., Chen, L.M., Chai, K.X., Chao, J., and Tomita, K. : Regulation of prostasin by aldosterone in the kidney. J. Clin. Invest., 109: 401-408, 2002

Yamakawa, K., Kitamura, K., Nonoguchi, H., Takasu, N., Miller, R.T., and Tomita, K. : Gα13 induces preproET-1 gene expression via JNK. Hypertens. Res., 25: 427-432, 2002

Kitamura, K. and Tomita, K. : Endothelin receptor antagonists prevent parathyroid cell proliferation caused by hypocalcemia in rats. Curr. Opin. Nephrol. Hypertens., 11: 411-415, 2002

2001年

Adachi, M., Kitamura, K., Miyoshi, T., Narikiyo, T., Iwashita, K., Shiraishi, N., Nonoguchi, H., and Tomita, K. : Activation of epithelial sodium channels by prostasin in Xenopus oocytes. J. Am. Soc. Nephrol. 12: 1114-1121, 2001

Kyuma, M., Ura, N., Torii, T., Takeuchi, H., Takizawa, H., Kitamura, K., Tomita, K., Sasaki, S., and Shimamoto, K. : A family with Lliddle's syndrome caused by a mutation in the β subunit of the epithelial sodium channel. Clin. Exp. Hypertens. 23: 471-478, 2001

1999年

Kitamura, K., Shiraishi, N., Singer, W.D., Handlogten, M.E., Tomita, K., and Miller, R.T. : Endothelin-B receptors activate Gα13. Am. J. Physiol. (Cell Physiol.), 276: C930-C937, 1999

1997年

Kitamura, K., Tomita, K., and Miller, R.T. : Inhibition of nitric oxide synthase activity and nitric oxide-dependent calcium influx in renal epithelial cells by cyclic adenosine monophosphate: Implications for cell injury. J. Am. Soc. Nephrol. 8: 558-568, 1997

1996年

Kitamura, K., Singer, W.D., Star, R.A., Muallem, S., and Miller, R.T. : Induction of inducible nitric-oxide synthase by the heterotrimeric G protein Gα13. J. Biol. Chem. 271: 7412-7415, 1996

Khair-El-Din, T., Sicher, S.C., Vazquez, M.A., Chung, G.W., Stallworth, K.A., Kitamura, K., Miller, R.T., and Lu, C.Y. : Transcription of the murine iNOS gene is inhibited by docosahexaenoic acid, a major constituent of fetal and neonatal sera as well as fish oils. J. Exp. Med. 183: 1241-1246, 1996

1995年

Xu, X., Kitamura, K. (equal contribution), Lau, K.S., Muallem, S., and Miller, R.T. : Differential regulation of Ca2+ release-activated Ca2+ influx by heterotrimeric G proteions. J. Biol. Chem. 270: 29169-29175, 1995

Kugi, M., Kitamura, K., Cottam, G.L., and Miller, R.T. : Expression of Gαi2 mimics several aspects of LPS priming in a murine macrophage-like cell line. J. Inflamm. 45: 175-182, 1995

Kitamura, K., Singer, W.D., Cano, A., and Miller, R.T. : Gαq and Gα13 regulate NHE-1 and intracellular calcium in epithelial cells. Am. J. Physiol. (Cell Physiol.), 268: C101-C110, 1995

1994年

Kitamura, K. and Miller, R.T. : Regulation of hormone-sensitive calcium influx by the adenylyl cyclase system in renal epithelial cells. J. Clin. Invest. 94: 328-336, 1994

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